Most recently Sullivan played the lead role of Detective Amy Lynch on "Shattered" for Global Television, opposite Callum Keith Rennie. Camille was nominated for a Canadian television Gemini Award for her portrayal of Francine Reardon, the volatile cocaine and alcohol addicted ex-wife of a west coast crime boss in the critically acclaimed "Intelligence," a television series from "DaVinci's Inquest" creator Chris Haddock. She played a lead role in "Mistresses," a drama pilot for Lifetime, written by Melissa Carter Newman, and based on the British series of the same name. Other television credits include three seasons of "DaVinci's Inquest," recurring roles on "Hellcats", "Reunion" and "Taken," and multiple guest starring and leading roles in both television series and movies.
Sullivan's past film projects include Carl Bessai's multiple award-winning dramatic feature film, "Normal." Her performance won her a Leo Award for Best Actress in a Feature Length Film. Other starring roles include "Mount Pleasant," written and directed by Ross Weber, "Mothers and Daughters," an improvised film directed by Carl Bessai -- for which she earned another Leo Award nomination -- and the Gary Burns film "A Problem with Fear." Camille also recently finished shooting Bessai's "Sisters & Brothers" . Next up, Sullivan can be seen as Detective Jo Rosati in season 2 of ABC/GLobal's hit series Rookie Blue.
O'Sullivan has performed in sell-out seasons in Ireland, New York, the UK, Australia (including the Sydney Opera House with her award winning shows and also with the ensemble off Broadway hit show and Olivier Award winning 'La Clique' (known as 'Absinthe' in America). She has performed her 'Dark Angel' show for a six week West End run at the Apollo Theatre London, the legendary Roundhouse, Hal Wilner's Rogues Gallery with Tim Robbins, Marianne Faithfull, Sarah Blasko and Todd Rundgren at the Sydney Festival 2010, supported Jools Holland tour including the Royal Albert Hall.
After being spotted by Ewen Bremner (Spud from Trainspotting) in La Clique in The Famous Spiegeltent , O'Sullivan co-starred as the vaudeville star Jane in the film Mrs Henderson Presents, directed by Stephan Frears, opposite Dame Judi Dench and Bob Hoskins. She and Will Young are also on the soundtrack to the movie. She has appeared singing with Damien Rice, Jack L, Duke Special, Tim Robbins and Shane MacGowan.
As much storyteller as singer, Camille has a respected international reputation for her dark dramatic interpretations of the songs of Jacques Brel, Nick Cave, Tom Waits, Dillie Keane, Kurt Weill, David Bowie, and Radiohead . The productions 'La Fille Du Cirque','The Dark Angel' and 'Chameleon" were self directed with the emphasis on inhabiting the character of each story,revealing different aspects emotionally dark and light, lending to her chameleon like quality on stage- In her early days she concentrated on more traditional 'narrative storytelling' with Eisler, Weill and chanteuse fayre Edith Piaf and says that she may have alienated some by making the switch to interpreting darker contemporary songs which originated, in the most part, from male artists:
“I feel it’s necessary to not just do things to please,” she says. “I sometimes worried about that in the past. I thought, ‘If I don’t want to alienate people, I shouldn’t perform difficult provocative dark songs’. But I would have given up if I’d stayed doing Dietrich and Piaf in a studied way, that cafe-cabaret version, where you’re making it easy instead of pushing yourself.”
In 1994,she performed in 'Jacques Brel is Alive and Well and Living in Paris' at University College, Dublin  which increased her passion for Brel's work, in particular the songs Amsterdam and Next, the latter being one of the climactic moments of her Spiegletent 2007 performance at the Edinburgh Festival Fringe, and both appearing on her 'Fille Du Cirque' album.
Both of these songs are told from a male perspective, with Next ('Au Suivant') telling the story of a young soldier who loses his virginity in a 'mobile army whorehouse, gift for the army, free of cost' and is haunted for the remainder of his life both by the horrors of war and by his disgust for the sexual experiences. However, O'Sullivan is not deterred from performing them, commenting that she sings them in the lowest key possible for her voice in order to retain the drama and tone of the originals, while finding a character within the song that she can inhabit, such as the prostitute an sailor in 'Amsterdam'.
In 2007 Camille played 'Beggar Woman' in the 'Best Opera Production' of 2007 (Irish Times Irish Theatre Award), Sondheim's 'Sweeney Todd' at The Gate Theatre, Dublin (“This production is a miracle…gripping and musically brilliant” Guardian).Camille performed in the Acoustic Tent at the Glastonbury Festival in 2008, Latitiude Festival 2009, Later With Jools 2008, Interview with David Frost 2010, Barbican Nick Drake tribute 2009 with Martha Wainright, Vashti Bunyan, Harper Simon, Stuart Murdoch and Blurs Graham Coxon, Barbican Brel evening with Marc Almond, Momus, Arno and Arthur H, and she also conducted a residency at the Queen's Hall, Edinburgh as part of the Festival Fringe.